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Best Museums in the U.S.: Exploring Art, Science, and History

November 14, 2025 By CityPASS

Museums serve as gateways to understanding our world. They're places where art speaks across centuries, science reveals nature's mysteries, and history comes alive through carefully preserved stories. Across the United States, these cultural institutions offer visitors the chance to connect with humanity's greatest achievements and most profound questions.

Whether you're drawn to masterpieces hanging in gallery halls, fossils that whisper tales of ancient life, or artifacts that chronicle pivotal moments in our collective past, America's top museums deliver experiences that educate, inspire, and stay with you long after you've left their doors.

Art Museums That Define Cultural Excellence

Art museums throughout the United States showcase collections that span millennia and continents, offering windows into human creativity at its finest. These institutions don't just display paintings and sculptures. They tell stories about movements, cultures, and the artists who shaped how we see the world. Here are a few of the best in the country to add to your bucket list.


The Art Institute of Chicago

The Art Institute of Chicago is among the nation's most celebrated art museums, housing an encyclopedic collection that ranges from ancient artifacts to contemporary installations. Visitors encounter iconic works like Grant Wood's "American Gothic" and Georges Seurat's "A Sunday on La Grande Jatte," alongside treasures from every major artistic period. The museum's modern wing, designed by Renzo Piano, provides a stunning architectural complement to the masterpieces within.


Museum of Modern Art (NYC)

The Museum of Modern Art in New York presents one of the world's finest modern art collections, including Vincent van Gogh's "The Starry Night" and Pablo Picasso's "Les Demoiselles d'Avignon." Recent expansions have created even more space to experience groundbreaking works that defined artistic movements throughout the 20th and 21st centuries. For those exploring the best museums in New York, MoMA represents an essential stop on any cultural itinerary.


San Francisco Museum of Modern Art

San Francisco Museum of Modern Art (SFMOMA) ranks among the best San Francisco museums for contemporary and modern art enthusiasts. Its seven floors showcase photography, painting, sculpture, and multimedia works that challenge conventional thinking. The museum's Living Wall — a vertical garden containing thousands of plants — adds natural beauty to your cultural exploration.


Denver Art Museum

Denver Art Museum captivates with both its holdings and its architecture. The Hamilton Building's dramatic angular design creates an unforgettable backdrop for exploring American Indian, Western American, and international art. The museum's commitment to interactive experiences makes it particularly welcoming for visitors new to art appreciation.

Science and Natural History Museums That Spark Wonder

Science and natural history museums transform learning into adventure, inviting visitors to explore everything from dinosaur fossils to the farthest reaches of space. Here are some of the top science and natural history museums to visit at some point in your life.


American Museum of Natural History (NYC)

The legendary American Museum of Natural History (AMNH) has captured imaginations since 1869. The moment you enter the Theodore Roosevelt Rotunda and encounter the towering Barosaurus defending its young from an attacking Allosaurus, you know you're somewhere special. The museum's dinosaur halls remain perpetual favorites, but don't overlook the stunning dioramas depicting wildlife in their natural habitats — created with such artistry that the animals seem ready to step out of their displays.

The Rose Center for Earth and Space houses the Hayden Planetarium, where shows transport viewers through cosmic phenomena. The Hall of Ocean Life features a 94-foot blue whale model suspended overhead, creating an unforgettable sense of the ocean's grandeur. With 45 permanent exhibition halls spanning cultures, natural history, and scientific discovery, planning your visit requires some strategy, but the experience rewards every moment spent exploring.


The Field Museum (Chicago)

The Field Museum combines serious scientific research with public engagement in ways that few institutions match. Make sure to stop by and see SUE, the most complete Tyrannosaurus rex fossil ever discovered. But the museum's treasures extend far beyond dinosaurs.

The Ancient Americas exhibition presents artifacts spanning 13,000 years, while the Ancient Egypt collection invites you inside a three-story mastaba tomb. The Grainger Hall of Gems displays dazzling specimens, including the 3,632-carat Chalmers Topaz. The Field Museum excels at connecting natural history with human culture, showing how our ancestors understood and interacted with the world around them.


Fernbank Museum of Natural History (Atlanta)

The Fernbank Museum of Natural History greets visitors with "Giants of the Mesozoic," a breathtaking display of life-size Argentinosaurus and Giganotosaurus locked in a dramatic encounter. This centerpiece sets the tone for a museum that blends prehistoric wonder with interactive discovery. Inside, the "NatureQuest" exhibit immerses children in ecosystems of treehouses and caves, while Reflections of Culture explores global traditions through textiles and artifacts.

Beyond the walls, WildWoods offers elevated walkways and interactive exhibits that lead into Fernbank Forest, a 65-acre old-growth sanctuary. With rotating exhibitions like "Ultimate Dinosaurs" and a Giant Screen Theater showcasing sweeping educational films, Fernbank connects Atlanta's urban energy to Earth's ancient past in unforgettable ways.


Griffin Museum of Science and Industry (Chicago)

Housed in the grand Beaux-Arts Palace of Fine Arts from the 1893 World's Columbian Exposition, the Griffin Museum of Science and Industry combines architectural splendor with scientific wonder. The moment you enter, you're stepping into the largest science museum in the Western Hemisphere, where history and innovation converge. Among its most iconic experiences is the U-505 Submarine, a captured German U-boat from World War II that visitors can explore inside and out. Nearby, the "Coal Mine" exhibit plunges guests into a simulated underground shaft, offering a gritty glimpse of industrial life.

The museum's interactive spirit shines in the "Numbers in Nature" exhibit, a dazzling mirror maze revealing mathematical patterns in the world around us, and "YOU! The Experience," where you can power a 13-foot Giant Heart with your own heartbeat or spin on a human-sized hamster wheel. Add in a Boeing 727 suspended overhead, a five-story wraparound theater, and the chance to control a 40-foot tornado, and you have a destination that transforms science into spectacle. Griffin MSI doesn't just display artifacts—it immerses you in the forces that shape our world.


Museum of Science (Boston)

Perched on the banks of the Charles River, the Museum of Science transforms complex ideas into hands-on experiences that spark curiosity. The moment you enter, the "Theater of Electricity" exhibit steals the show with its indoor lightning storms, while the "Colossal Fossil: Triceratops Cliff" exhibit offers an awe-inspiring glimpse into prehistoric life. Nearby, the "Hall of Human Life" explores what it means to be human in an era of rapid change, and the "Sound Lab" connects visitors to the natural world through interactive displays overlooking the river.

Beyond the exhibit halls, the Charles Hayden Planetarium launches guests into the cosmos with immersive star shows, while the Mugar Omni Theater surrounds audiences with a five-story IMAX dome for unforgettable journeys through science and nature. With over 700 interactive exhibits, live presentations, and experiences like the "Arctic Adventure" exhibit and the "Engineering Design Workshop" exhibit, the Museum of Science doesn't just teach science—it invites you to live it.

Museums That Bring History and Culture to Life

History and culture museums preserve narratives that define who we are, offering profound insights into the struggles, triumphs, and transformations that have shaped society. These institutions challenge us to remember, reflect, and grow.


National Center for Civil and Human Rights (Atlanta)

The National Center for Civil and Human Rights connects the American Civil Rights Movement to contemporary human rights struggles worldwide. Through immersive exhibits and authentic artifacts, visitors confront difficult truths about segregation, discrimination, and the ongoing fight for justice. The "Lunch Counter" exhibit recreates the hostile environment civil rights activists faced during sit-ins, creating a visceral understanding that reading alone cannot achieve.

The museum also showcases Martin Luther King Jr.'s personal papers and belongings, offering intimate glimpses into the life of one of history's most influential leaders. By linking past civil rights battles with current global human rights issues, the museum demonstrates how historical knowledge informs present-day activism. Among the best historical museums in the country, this institution doesn't just document the past. It inspires action for the future.


Museum of Pop Culture (Seattle)

MOPOP takes a refreshingly different approach to cultural preservation by celebrating popular culture's impact on society. Located in Frank Gehry's spectacular, undulating building, the museum explores music, film, video games, and science fiction through interactive exhibits that encourage hands-on participation.

The Science Fiction and Fantasy Hall of Fame celebrates storytelling that has shaped how we imagine possible futures. Play instruments in the "Sound Lab" exhibit, record in a studio, or explore costume and prop collections from beloved films and television shows. This celebration of creativity in its many forms makes MOPOP essential for understanding how art and entertainment reflect and shape contemporary life.

Smart Tips for Visiting U.S. Museums

Weekday mornings typically see smaller crowds, allowing more intimate engagement with exhibits. Many institutions offer extended hours on specific evenings, providing opportunities to explore in a quieter atmosphere.

Museum fatigue is real, as attempting to see everything in one visit often means truly experiencing nothing. Prioritize what genuinely interests you.

For travelers planning to visit multiple attractions, CityPASS tickets offer an efficient way to access the top museums in cities like New York, Chicago, Atlanta, Seattle, and other major destinations while saving significantly on admission costs. These tickets eliminate separate ticket lines at each location, streamlining your cultural adventures.

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